Renal- At a Glance

28/04/2013 by admin | Renal
  1. Drugs excreted by kidney which can accumulate in renal failure: digoxin, lithium, morphine and metabolites, penicillins, gentamicin, vancomycin, erythromycin, acyclovir
  2. Drugs which require higher doses in renal failure: frusemide
  3. Drugs that can exacerbate metabolic effects in pre-existing renal failure: spironolactone (=hyperkalaemia), corticosteroids (=uraemia), NaCl (=water retention)
  4. Drugs which can produce idiosyncratic renal toxicity: NSAIDs, penicillins, gold, penicillamine
  5. Drugs which can reduce renal function and should be used with caution in renal failure: NSAIDs, ACEi, cyclosporine, acyclovir, contrast media
  6. Drugs which can produce renal failure in overdose: gentamicin, paracetamol, ethylene glycol


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