Benign tumours and related conditions
Hemangioma (=benign, children, strawberry lesion on face/scalp/CNS/liver/mucous membranes, can result of trauma [granuloma pyogenicum]).
- Especially in children.
- Make up approximately 7% of all benign tumours.
- o Occur mostly in skin and mucous membranes
- o Well-defined, encapsulated aggregates of capillaries
- o May be thrombosed
Juvenile capillary (strawberry) hemangioma
- o Present at birth on the face and scalp
- o Grow rapidly for the first few months, then regress and disappear by the age of 5
- o Large, cavernous, vascular channels that are not encapsulated
- o Involve skin, mucous membranes, the central nervous system and the liver
- o Ulcerated version of capillary hemangioma
- o Caused by trauma
- o Composed of capillaries with oedema, inflammatory cells and granulation tissue
- Painful tumours of the glomus body = receptor in the smooth muscle of arteries that is sensitive to temperature
- Usually found in fingers or nail beds.
Hemangioendothelioma: Intermediate-grade tumours
- Neoplasms that show both benign and malignant characteristics.
- Consist of vascular channels with masses of spindle-shaped plump cells of endothelial origin
Angiosarcoma: Malignant tumours
- Rare but very aggressive
- Found in skin, breasts, liver and spleen
- Especially in elderly.
- There are small, red nodules that changes into large white masses in which cells of all differentiations are found.
- Malignant tumour of pericytes occurring in the lower extremities or in the retroperitoneum.
- About half of these metastasise.
- Malignant tumour of unknown origin.
- Purple plaques are found in skin, mucosa or viscera.