- This is treatment resistant HTN (2% of HTN), with hypokalaemia. Occasionally potassium is normal if sodium intake is low.
- o Benign adenoma (=Conn’s syndrome = [an aldosterone producing adenoma of the adrenal gland] – 66% of hyperaldosteronism)
- o Bilateral adrenal hyperplasia (30%)
- o Rarely glucocorticoid remedial aldosteronism or adrenal carcinoma
- o Lab: hypokalaemia, increased urinary potassium, supressed renin and elevated aldosterone
- o Imaging: CT of adrenals, radio-labelled cholesterol scan and adrenal vein sampling
- o Surgery = adrenalectomy for Conn’s adenoma
- o Aldosterone antagonists (spironolactone/amiloride) for other causes