• Calcium pyrophosphate deposition disease (CPDD)

    by  • 30/06/2013 • Rheumatology

    1. Inflammatory arthritis due to deposition of pyrophosphate crystals, associated with OA, hyperparathyroidism, and haemochromatosis.
    2. P/c: less severe than gout, difficult to differentiate from other athritides. Knee, wrist, shoulder affected, maybe triggered by inter-current illness, and metabolic disturbance.
    3. Ix: chondrocalcinosis maybe seen on Xray (calcification of articular cartilage), joint crystals present.
    4. Mx: tx like acute gout. Consider referral to rheum for DMARDs.
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